RamanRxn2™ Hybrid Analyzer

The RAMANRXN2™ HYBRID  in situ analyzer provides the capability of several different Raman analyzers in a single system.  The analyzer incorporates internal calibration and diagnostics to ensure the validity of each analysis. This approach allows Kaiser analyzers to support robust chemometric analyses and calibration transfer between analyzers.

When combined with the latest version of the iC Raman™ software, the RAMANRXN2™ HYBRID analyzer represents the most advanced, flexible analyzer for Raman methods development and reaction analysis providing both qualitative and quantitative Raman measurements.

When implemented as directed with the latest compliant version of the iC Raman™ data acquisition software, this analyzer meets the needs of both GLP and GMP governed areas within the pharmaceutical and biopharmaceutical industry for both PAT and QbD applications.
The RAMANRXN2™ HYBRID analyzer features Hybrid (micron and mm) probe capability, high spectral resolution, as well as transportability.  The RAMANRXN2™ models have an optional ergonomic trolley which includes built-in probe and optic storage, a routine-analysis sample compartment, fiber storage, and the analyzer control system.

Millimeter to micron sampling versatility is accomplished by coupling the RAMANRXN2™ HYBRID analyzer with Kaiser's MR Probe or the PhAT probe heads for non-contact or direct insertion sampling. The RAMANRXN2™ HYBRID analyzer is the first Raman analyzer to feature both traditional small spot Raman sampling and PhAT-based wide area Raman sampling.

  • Pharmaceutical Formulations Development: Blending, Granulations, Drying
  • Pharmaceutical API Development: Reaction Chemistry, Yield, Form ID
  • Polymerization
  • Polymer Blending
  • Extrusion Monitoring
  • Biologics / Bioprocessing / Biotech
  • Chemical
Analyzer Benefits
  • mm to micron Sampling
  • Optimized Liquids Analysis Mode
  • Optimized Solids Analysis Mode
  • Qualitative Raman and Quantitative Raman Analysis
  • Laboratory, Scale-up, and Pilot-plant Compatible
RamanRxn2™ Hybrid Analyzer
Measurement: Raman
Laser Wavelength: 785nm
Spectral Coverage: 150-1875 cm-1 (785nm)
Temperature: 15°C (Min) / 30°C (Max)
Relative Humidity: 20 to 80%, Non-condensing
Electrical Data - Base Unit:
Input Voltage: 110-240 VAC,
50-60Hz Standard
Max Power: <400 Watts Max (startup),
<150 Watts Typical
User Interface: Approved PC Operating
Windows 7, 32-bit / 64-bit Professional (software dependent)
Physical - Base Unit:
Enclosure Type: Painted Steel, Aluminum,
and Plastic
Mounting: Benchtop / Cart
Dimensions: 28 cm (l) x 62 cm (d) x 48 cm (h)
11” x 24.5” x 19”
(benchtop model)

63.5 cm (l) x 76 cm (d) x 142 cm (h)
25” x 30” x 56”
(cart-mounted model)
Weight: 68 lbs / 31 kg (benchtop model)

195 lbs / 88.5 kg (cart-mounted model)
Number of Probes: Hybrid – One PhAT
and One Non-PhAT Type
Product Resources
Title Category Format ID#  
RamanRxn2 Hybrid™ Analyzer Product Flyers PDF PF0015
PhAT Probe for Solids Analysis Product Flyers PDF PF0024
Raman Spectroscopy in Polymer Applications from Laboratory Discoveries to Large-scale Production Research Posters PDF POST007
Current Trends in Polymer Raman Spectroscopy: Quality, Efficiency, and Safety White Papers PDF WPP0002
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