Bioprocess RamanRxn2™
Multi-channel Analyzer

The RAMANRXN SYSTEMS™ suite of analyzers has set the standard for analyzing, monitoring, and controlling bioprocesses since its introduction in 2009. Raman spectroscopy provides the chemical specificity of a mid-IR analyzer with the ease of sampling of a near-IR analyzer.

The RAMANRXN2™ analyzer is ideally suited for applications in Development scale (10ml – 20L), Pilot scale (50L-500L), and Manufacturing scale (500L – 15,000L+) bioreactors. The ability to scale with the bioprocess enables these analyzers to monitor, measure, and optimize the bioprocess throughout its life cycle. The multi-channel RAMANRXN2™ enables the use of a single-analyzer in support of up to 4 probes, simultaneously utilized in as many bioprocesses. The RAMANRXN2™ 4-channel Raman analyzer operates sequentially allowing both fast analysis per channel and programmable channel integration.

The RAMANRXN2™ fiber-coupled multi-channel Raman analyzer addresses the novel application environment associated with bioprocessing. This analyzer can be combined with the latest compliant version of the iC Raman™ data acquisition software, Enterprise Historian, or Legacy DCS to comply with GLP/GMP guidelines of the bioprocess industry and both PAT/QbD initiatives.

Applications
  • Cell Culture
  • Fermentation
  • Purification
  • Process Development to Pilot to Manufacturing
Features
  • High Performance Spectroscopy
  • In Situ Continuous Bioprocess Measurements
  • Enabled for up to 4 Bioreactors
  • Designed for the Bioprocess Environment
Product Resources
Title Category Format ID#  
Raman-Based Nutrient Control in Bioprocessing Optimizes Viable Cell Density and Protein Glycation Raman Application Note PDF AN328
Raman WorkStation Featuring Dr. Sean Gilliam Webinar Presentations PowerPoint WP0006
Raman spectroscopy for in-line, real-time fermentation monitoring PDF POST006
Raman spectroscopy technologies enabling in situ real-time bioprocess monitoring PDF POST008
Comparison of NIR and Raman Spectroscopy for Online Glucose Predictions PDF WPP0004
In situ Raman for monitoring and controlling bioprocesses PDF WP0006
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