Raman Spectroscopy
New Raman Products

NEW PRODUCT RELEASE
PhAT System™ Raman Analyzer: New PAT Tool for Solids Analysis

ANN ARBOR, MI (Dec 28, 2005) - KOSI is pleased to introduce the newest member of the RamanRxn Systems™ suite of Raman analyzers: the PhAT System. 

The PhAT System revolutionizes solids analysis using Raman spectroscopy by eliminating sampling irreproducibility and focusing sensitivity, by measuring a representative volume of sample, and by offering the benefits of low laser power set below the ANSI recommended exposure limit
for skin.

The specificity of Raman spectroscopy towards crystalline materials has proven to be critical for measurements of API in complex formulations. Low dosage measurements, polymorphic form identification and amorphous form content are now possible either in-situ or at-line.  Further applications benefiting from the PhAT System approach are blending, granulation, coating, and tabletting.

The PhAT System redefines the standard for reliability, stability, and simplicity for Raman spectroscopic analysis of solids whether in the R&D laboratory, analytical, QC/QA or manufacturing.

Go to PhAT System product info page

 

ANN ARBOR, MI (October 20, 2005) - In response to the FDA’s recently announced Process Analytical Technology (PAT) initiative and incorporating input from our existing 24/7 Process Analytical chemistry (PAC) customers, KOSI is pleased to introduce the new RamanRxn3 process Raman analyzer.  The RamanRxn3 is a self-calibrating, self-diagnosing, fiber-coupled Raman analyzer designed to meet the needs of the process analytics, chemical, and polymers markets as well as the PAT pharmaceutical market.

Versatility was a key goal when developing the feature set for the RamanRxn3. The analyzer is contained in a stainless steel enclosure rated for installation in classified locations.  The system can be mounted either permanently on a wall or on a trolley so it can be used in the laboratory for methods development or in the pilot plant for process understanding or in production for process monitoring and control.  Sampling versatility is accomplished by coupling the RamanRxn3 with either the MR Probe or the Pilot™ line of process probes for non-contact or direct insertion sampling.  A single RamanRxn3 analyzer may be configured to monitor multiple process locations.

The RamanRxn3 analyzer incorporates advanced self-calibration and self-diagnostics to ensure the validity of each analysis.  The analyzer’s precision allows both advanced chemometric analyses and traditional univariate methods to be used.

For application development, KOSI’s HoloGRAMS™ 4.1, HoloReact™, and HoloPro™ software packages are available as well as support for third-party chemometrics packages such as GRAMS/AI® and Matlab®.  Once data has been collected by the RamanRxn3 HoloPro can be used to communicate results to the plant DCS for control or logging purposes.

Go to RamanRxn3 product info page

 

Identifying an Intermedate in Microwave-Assisted Organic Reaction

Surfactant-Assisted Dispersion of Single-Walled Carbon

RamanRxn3 PAT Analyzer: A New PAT Analyzer for the 21st Century

PhAT System Raman Analyzer:New PAT Tool for Solids Analysis

Go to Raman Review Issue1, 2005