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Kaiser Announces the RAMAN WORKSTATION™ Raman Analyzer

ANN ARBOR, MI - Kaiser is pleased to announce the release of a new generation RAMAN WORKSTATION™ Raman analyzer.

Formulation development remains a critical step in the development of a new drug product. Each step represents a risk to product quality as each step exposes the active pharmaceutical ingredient to potential change and / or dilution. In order to evaluate process induced transformations in situ, Kaiser developed PhAT technology in 2005. In addition to in situ testing it is also possible to use Raman for unit doseage confirmation by using transmission Raman approaches to evaluate content uniformity. While transmission Raman has the potential to provide whole tablet quantitation it cannot provide detailed information on the product surface or indications of clumping of the active pharmaceutical ingredient. In order to obtain this type of information a Raman microscope is typically used. Thus in order to obtain detailed information on the formulation process it has been necessary for a company to invest in and use two different types of Raman analyzers.

The RAMAN WORKSTATION™ Raman analyzer addresses both these needs in a single analyzer. Raman images from the surface and the bulk can be provided at either low or high spatial resolution without removing the tablet. In transmission modes the RAMAN WORKSTATION™ Raman analyzer can be used to evaluate tablet’s or capsule’s content uniformity.

Utilizing a RAMAN WORKSTATION™ Raman analyzer a formulation's critical quality attributes during the formulation development phase can be determined. This information can be fed back to the manufacturing team to ensure an optimized deployment of an in situ RAMAN WORKSTATION™ PhAT-capable analyzer in order to monitor and control critical parameters, thus ensuring optimized product quality while meeting the goals of the Quality by Design (QbD) initiative.

The RAMAN WORKSTATION™ Raman analyzer meets the needs of the pharmaceutical and solids catalyst markets where solids formulations development is critical. The combination of the capabilities of a wide area Raman analyzer and a Raman microscope make the analyzer attractive in term of both analyzer ROI and analyst time.

About Kaiser Optical Systems
Kaiser Optical Systems, Inc., a wholly owned subsidiary of Rockwell Collins (NYSE: COL), is a leader in the design and production of holographic optical elements, Raman analyzers and components for spectroscopy. The company was formed in 1979 and has over 18 years of experience in Raman spectroscopy with customers located around the world. Additional company and product information is available at www.kosi.com.

Rockwell Collins (NYSE: COL) is a pioneer in the development and deployment of innovative communication and aviation electronic solutions for both commercial and government applications. Our expertise in flight deck avionics, cabin electronics, mission communications, information management, and simulation and training is delivered by 20,000 employees, and a global service and support network that crosses 27 countries. To find out more, please visit www.rockwellcollins.com.

For Immediate Release

For Kaiser
Contact Ian R. Lewis
Kaiser Optical Systems, Inc.
Address 371 Parkland Plaza
Ann Arbor, MI 48103 USA
Tel + 1 734 665 8083
Fax + 1 734 665 8199
Email marketing@kosi.com
Internet www.kosi.com