The New Sampling/Sensor Initiative (NeSSI) is a global and open initiative originally proposed by a consortium of industry (end users/vendors) and academia. The NeSSI initiative has promoted the acceptance and implementation of modular lego-like flow components.
These flow-components termed Generation I are based on the ANSI/ISA SP76.00.2002 miniature, modular mechanical standard. The ANSI/ISA standard is referenced by the International Electrotechnical Commission in publication IEC 62339-1:2006. The adoption of a standard allows interchangeability of components between different manufacturers. The availability of NeSSI interfaces for Kaiser's liquid and gas-phase probes provides a convenient plug-and-play platform for development of continuous flow chemistry in support of high-yield, safe, green chemical pathways using in situ Raman for critical process measurements.