Raman Educational Webinars

Kaiser hosts a series of complimentary webinar presentations which demonstrate Raman Spectroscopy-based solutions. Hear from real customers and their success stories using Kaiser Raman analyzers and instruments. Examples of Research Raman, Analytical Raman, Process Raman, In Situ Raman, Industrial Raman, Remote Raman, and Raman Imaging and Microscopy are available during these sessions. We invite you to register for an upcoming webinar of interest, or view previous archives.  Kaiser Webinar Archives are available in the sidebar -- see what you've been missing!

Real Customers - Their Applications, Raman Solutions

Single Probe Multi-purpose In Situ Monitoring and Control
At our site we have integrated two Kaiser Raman systems into the Pilot Plant scale bioreactors to investigate their performance and validate methods for measuring glucose, lactate, and other process metabolites in real time. In conjunction with a preferred vendor, an application and technology assessment was performed using a combination of published literature, process knowledge, and technical expertise. A series of candidates for assessment were identified.

At our facility the bioreactors are fitted with an aseptic automated sampling (AAS) valve to deliver offline metabolite analysis at regularly scheduled intervals throughout the duration of the batches, enabling 24 hour sampling and more than doubling the amount of comparative samples that are collected. Successful data collection and nutrient determination from the Kaiser Raman enables real time quantification of metabolites and the ability to control nutrient feeds through automated feedback loops. Additional studies to examine protein concentration in downstream processing and correlate data to in process upstream measurements are also expected.

During the webinar, I will provide a brief overview of the biologics production process, and discuss the feasibility assessment of both NIR and Raman for metabolite quantification. This includes models based on inline and offline data as well as the development of control strategies. Lastly, the development of real time protein quantification from bioreactor process samples will be discussed.

AIR DATE: June 20, 2013

PRESENTER INFO
Name: Tara L. Barreira
Title: Scientist, Bioprocess Research and Development
Company: Pfizer

Search Webinar Archives

  • Archives
  • 2018
    • TITLE: Raman for Bioprocessing
      AIR DATE: 2018-07-11
      PRESENTER INFO
      Name: Nobel Vale
      Title: Research Scientist II
      Company: Bristol-Myers Squibb
      Name: Justin Moretto
      Title: Bioprocessing Consultant
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Raman Spectroscopy for Monitoring Cervical Remodeling in Pregnant Women in Vivo
      AIR DATE: 2018-05-01
      PRESENTER INFO
      Name: Dr. Christine O'Brien
      Title: Research Associate
      Company: Washington University in St. Louis, Department of Radiology
      MORE INFO
    • TITLE: Comparison of NIR and Raman Spectroscopy for Online Glucose Predictions Using a Shake Flask Model System
      AIR DATE: 2018-01-30
      PRESENTER INFO
      Name: Bence Kozma
      Company: Budapest University of Technology and Economics
      MORE INFO
  • 2016
    • TITLE: Raman Spectroscopy Part IV: Raman in the Plant Environment: The Final Challenges
      AIR DATE: 2016-06-02
      PRESENTER INFO
      Name: Dr. John Wasylyk
      Principal Scientist
      Bristol-Myers Squibb
      Name: Mark Lindrud
      Senior Scientist
      Bristol-Myers Squibb
      MORE INFO
    • TITLE: Development of a Continuous Process for an Oxidative Nitration Reaction of a Nitroalkane
      AIR DATE: 2016-03-31
      PRESENTER INFO
      Name: Dr. David Ford
      Title: Chemist
      Company: Nalas Engineering
      MORE INFO
  • 2015
    • TITLE: Utilization of Raman Spectroscopy for Primary and Secondary Pharmaceutical Development
      AIR DATE: 2015-05-14
      PRESENTER INFO
      Name: Dr. Allyson McIntyre
      Title: Senior Scientist, PAT Specialist in Global Chemical Development
      Company: AstraZeneca
      MORE INFO
    • TITLE: From Development to Plant Implementation of Raman Methods: Strategy, Challenges, and Solutions
      AIR DATE: 2015-04-23
      PRESENTER INFO
      Name: Dr. John Wasylyk
      Title: Principal Scientist
      Company: Bristol-Myers Squibb
      Name: Robert Wethman
      Title: Senior Research Scientist
      Company: Bristol-Myers Squibb
      MORE INFO
  • 2014
    • TITLE: Raman Spectroscopy with Synchrotron X-ray-based Techniques
      AIR DATE: 2014-12-04
      PRESENTER INFO
      Name: Dr. Valerie Briois
      Title: Beamline Manager of the ROCK Beamline (Rocking Optics for Chemical Kinetics)
      Company: SOLEIL Synchrotron
      MORE INFO
    • TITLE: Kaiser Raman for In Situ Measurement of Nutrients and Metabolites within a Mammalian Cell Culture Application
      AIR DATE: 2014-08-28
      PRESENTER INFO
      Name: Dr. Hamidreza Mehdizadeh
      Title: Senior Scientist
      Company: Pfizer
      Name: Maryann Cuellar
      Title: Applications Specialist
      Company: Kaiser Optical Systems
      MORE INFO
  • 2013
    • TITLE: Raman Spectroscopy in the Pharmaceutical Industry
      Part 2: Reaction Monitoring and Qualification
      AIR DATE: 2013-12-12
      PRESENTER INFO
      Name: Dr. John M. Wasylyk
      Title: Principal Scientist
      Company: Bristol-Myers Squibb
      MORE INFO
    • TITLE: Sensitivity-Enhanced Transmission Raman Spectroscopy
      AIR DATE: 2013-10-17
      PRESENTER INFO
      Name: Dr. Michael J. Pelletier
      Title: Associate Research Fellow in QbD Methods Dev Group
      Company: Pfizer
      MORE INFO
    • TITLE: Integration of Real-time Raman Measurements Optimizes DoE in Benchtop Bioreactors
      AIR DATE: 2013-07-24
      PRESENTER INFO
      Name: Larry West
      Title: Sr. Bioprocess Consultant
      Company: Kaiser Optical Systems, Inc.
      Name: Dr. Falk Schneider
      Company: DASGIP GmbH an Eppendorf Company
      MORE INFO
    • TITLE: Integration of Real-time Raman Measurements Optimizes DoE in Benchtop Bioreactors
      AIR DATE: 2013-07-24
      PRESENTER INFO
      Name: Larry West
      Sr. Bioprocess Consultant,
      Kaiser Optical Systems, Inc.

      Dr. Falk Schneider
      Managing Director,
      DASGIP GmbH
      an Eppendorf Company
      MORE INFO
    • TITLE: Single Probe Multi-purpose In Situ Monitoring and Control
      AIR DATE: 2013-06-20
      PRESENTER INFO
      Name: Tara L. Barreira
      Title: Scientist, Bioprocess Research and Development
      Company: Pfizer
      MORE INFO
    • TITLE: Validating Transcutaneous Raman Spectroscopy in Human Subjects
      AIR DATE: 2013-04-11
      PRESENTER INFO
      Name: Dr. Francis Esmonde-White
      Title: Research Area Specialist Lead, Dept of Chemistry
      Company: University of Michigan
      MORE INFO
    • TITLE: Raman Testing of Amorphous Silicates and Zeolites
      AIR DATE: 2013-03-28
      PRESENTER INFO
      Name: Dr. Istvan Halasz
      Title: Principal Chemist and Special Analytical Group Supervisor
      Company: PQ Corporation
      MORE INFO
    • TITLE: Monitoring Emulsion Polymerization Using Raman Spectroscopy
      AIR DATE: 2013-01-10
      PRESENTER INFO
      Name: Dr. Serena Stephenson
      Company: Dow Chemical Company
      MORE INFO
  • 2012
    • TITLE: Kaiser Raman: The Ultimate in Sampling Flexibility for Solids, Liquids, and Gases
      AIR DATE: 2012-06-28
      PRESENTER INFO
      Name: Dr. Sean Gilliam
      Title: Product Specialist
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Application of Raman Spectroscopy for Process Control and Understanding in the Pharmaceutical Industry - Part One: Lab and Plant Applications
      AIR DATE: 2012-04-05
      PRESENTER INFO
      Name: Dr. John M. Wasylyk
      Title: Principal Scientist
      Company: Bristol-Myers Squibb
      MORE INFO
  • 2011
    • TITLE: Raman Spectroscopy for In-line Monitoring of Pharmaceutical Hot-melt Extrusion Processes
      AIR DATE: 2011-10-20
      PRESENTER INFO
      Name: Dr. Thomas De Beer
      Title: Professor of Process Analytical Technology
      Company: University of Ghent
      MORE INFO
    • TITLE: Non-invasive Raman Analysis of Pharmaceutical Tablets and Powders
      AIR DATE: 2011-06-23
      PRESENTER INFO
      Name: Dr. David Littlejohn
      Title: Professor and Associate Deputy Principal for Research
      Company: University of Strathclyde
      MORE INFO
    • TITLE: Spatially Off-set and Transmission Raman Spectroscopy, Imaging, and Tomography in Light Scattering Media
      AIR DATE: 2011-05-19
      PRESENTER INFO
      Name: Dr. Matthew Schulmerich
      Title: Department of Defense Postdoctoral Fellow
      Company: University of Illinois
      MORE INFO
    • TITLE: Raman Spectroscopic Fingerprint of Intermediates in Biotechnological Reactions - A Multimodal Spectroscopic Approach
      AIR DATE: 2011-04-14
      PRESENTER INFO
      Name: Dr. Rudolf W. Kessler
      Title: Professor of Chemistry
      Company: Reutlingen University
      MORE INFO
    • TITLE: Dispersive Raman Spectroscopy - A Powerful Tool Within the Development of Crystallization and Drying Processes for Pharmaceutical Compounds
      AIR DATE: 2011-03-24
      PRESENTER INFO
      Name: Dr. Martin Feth
      Title: Head of Laboratory in Chemical Development and Physical Quality of API
      Company: Sanofi-Aventis Deutschland GmbH
      MORE INFO
    • TITLE: Monitoring Homogeneity Using Raman Spectroscopy in Inhalation Products
      AIR DATE: 2011-02-17
      PRESENTER INFO
      Name: Dr. Chanda Yonzon
      Title: Associate Principal Scientist
      Company: Merck & Co
      MORE INFO
  • 2010
    • TITLE: Transmission Raman Spectroscopy: Where Are We Looking, What Are We Seeing?
      AIR DATE: 2010-11-30
      PRESENTER INFO
      Name: Dr. Neil Everall
      Title: Company Research Associate
      Company: Intertek MSG
      MORE INFO
    • TITLE: Real Time Release Testing of Pharmaceutical Drug Products: How Does Raman Measure Up?
      AIR DATE: 2010-09-30
      PRESENTER INFO
      Name: Dr. Manoharan Ramasamy
      Title: Principal Scientist and PAT Leader
      Company: Merck & Co, Inc
      MORE INFO
    • TITLE: Petrochemical Applications of In-Situ Gas-Phase Raman Spectroscopy
      AIR DATE: 2010-09-09
      PRESENTER INFO
      Name: Dr. George Vickers
      Title: Research Associate
      Company: BP America
      MORE INFO
    • TITLE: Discovery and Characterization of Tetraalkylammonium Polybromides with Raman Spectroscopy
      AIR DATE: 2010-07-15
      PRESENTER INFO
      Name: Dr. Shawn Chen
      Title: Senior Chemist
      Company: Dow Chemical
      MORE INFO
    • TITLE: Application of Raman for Improved Biofuel Processing
      AIR DATE: 2010-06-24
      PRESENTER INFO
      Name: Dr. Brian Marquardt
      Title: Senior Principal Engineer
      Company: Applied Physics Laboratory, University of Washington
      MORE INFO
    • TITLE: Multichannel Reaction Monitoring with iC Raman™ 4.1
      AIR DATE: 2010-05-20
      PRESENTER INFO
      Name: Maryann Cuellar
      Title: Product Specialist
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Closed Loop Control of Titanium Dioxide Production Using Process Raman Spectroscopy
      AIR DATE: 2010-04-22
      PRESENTER INFO
      Name: Dr. Neil Everall
      Title: Company Research Associate
      Company: Intertek MSG
      MORE INFO
    • TITLE: The Role of Raman Microscopy in Polymorph Screening
      AIR DATE: 2010-03-25
      PRESENTER INFO
      Name: Sarah Vallance
      Title: Research Scientist, Solid Form Sciences
      Company: GlaxoSmithKline
      MORE INFO
    • TITLE: Application of Raman Spectroscopy to Solid-state Characterization During Early Drug Development
      AIR DATE: 2010-03-11
      PRESENTER INFO
      Name: Dr. Sachin Lohani, Solid-state Characterization Expert, Merck & Company
      MORE INFO
    • TITLE: Polarized Raman Scattering: A Powerful Tool for Characterization of Orientation
      AIR DATE: 2010-02-25
      PRESENTER INFO
      Name: Dr. Bruce Chase
      Title: Research Professor
      Company: University of Delaware and CTO of Pair Technologies LLC
      MORE INFO
    • TITLE: Using iC Raman™ for Process Development
      AIR DATE: 2010-01-28
      PRESENTER INFO
      Name: Greg Gervasio
      Title: Process Analytical Technology Professional Engineer
      Company: GlaxoSmithKline
      MORE INFO
    • TITLE: Concomitant Nucleation of Polymorphs on Engineered Surfaces
      AIR DATE: 2010-01-14
      PRESENTER INFO
      Name: Dr. Allan Myerson
      Title: Professor of Engineering
      Company: Department of Chemical and Biological Engineering at the Illinois Institute of Technology (IIT)
      MORE INFO
  • 2009
    • TITLE: Application of Raman Spectroscopy for Pharmaceutical Process Understanding
      AIR DATE: 2009-12-03
      PRESENTER INFO
      Name: Dr. Saly Romero-Torres
      Title: Principal PAT Scientist
      Company: Pfizer
      MORE INFO
    • TITLE: Vibrational Spectroscopy and Microspectroscopic Imaging: Introduction and Applications to Skin Pharmacology and Wound Healing
      AIR DATE: 2009-11-24
      PRESENTER INFO
      Name: Dr. Richard Mendelsohn
      Title: Professor of Chemistry
      Company: Rutgers University
      MORE INFO
    • TITLE: Quantitative Gas-phase Analysis Using the Kaiser AirHead™ Probe
      AIR DATE: 2009-10-29
      PRESENTER INFO
      Name: Dr. Pat Wiegand
      Title: Product Specialist
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Monitoring Zeolite Syntheses Using In-Situ Raman Spectroscopy
      AIR DATE: 2009-10-15
      PRESENTER INFO
      Name: Dr. Tom Mezza
      Title: Sr. Principle Research Scientist
      Company: UOP LLC
      MORE INFO
    • TITLE: Kaiser RamanRXN2™ 1000 Webinar
      AIR DATE: 2009-09-17
      PRESENTER INFO
      Name: Maryann Cuellar
      Title: Product Specialist
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Non-invasive and Minimally Invasive Raman Spectroscopy of Musculo-skeletal Tissue: A Multidisciplinary Approach
      AIR DATE: 2009-06-04
      PRESENTER INFO
      Name: Dr. Michael D. Morris
      Title: Professor of Chemistry
      Company: University of Michigan
      MORE INFO
    • TITLE: Raman Spectroscopy as a PAT Tool for Coating
      AIR DATE: 2009-05-07
      PRESENTER INFO
      Name: Dr. Peter Kleinebudde
      Title: Professor at the Institute of Pharmaceutics and Biopharmaceutics
      Company: Heinrich-Heine-University
      MORE INFO
    • TITLE: Using in-situ Raman for Improved Process Understanding in Development of a Crystallization Process
      AIR DATE: 2009-04-23
      PRESENTER INFO
      Name: Dr. Jun Chen
      Title: Principal Scientist
      Company: GlaxoSmithKline
      MORE INFO
    • TITLE: Analytical Data: the Good, the Bad, and the Ugly
      AIR DATE: 2009-04-02
      PRESENTER INFO
      Name: Dr. Pat Wiegand
      Title: Kaiser Product Specialist
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Transmission Raman Spectroscopy for Quantitative Analysis of Pharmaceutical Solids
      AIR DATE: 2009-02-19
      PRESENTER INFO
      Name: Anders Sparén
      Title: Associate Principal Scientist
      Company: AstraZeneca
      MORE INFO
    • TITLE: ATEX
      AIR DATE: 2009-02-05
      PRESENTER INFO
      Name: Joe Slater
      Title: Manager of Product Development
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Petrochemical Gas / Liquid Analysis - A New Frontier for On-line Raman Spectroscopy
      AIR DATE: 2009-01-29
      PRESENTER INFO
      Name: Dr. Peter van Vuuren
      MORE INFO
    • TITLE: Introduction to iC Raman™ V3.0
      AIR DATE: 2009-01-15
      PRESENTER INFO
      Name: Maryann Cuellar
      Title: Product Specialist
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
  • 2008
    • TITLE: Application of Dispersive Raman Spectroscopy During Drug Development
      AIR DATE: 2008-12-09
      PRESENTER INFO
      Name: Dr. Brigida Allieri
      Title: Principal Scientist
      Company: GlaxoSmithKline
      MORE INFO
    • TITLE: Kaiser Raman WorkStation™ with Dr. Sean Gilliam
      AIR DATE: 2008-11-12
      PRESENTER INFO
      Name: Dr. Sean Gilliam
      Title: Product Specialist
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Mechanistic Basis for Effective Cocrystal Screening Methods
      AIR DATE: 2008-10-23
      PRESENTER INFO
      Name: Dr. Nair Rodriguez-Hornedo
      Title: Associate Professor of Pharmaceutical Sciences
      Company: University of Michigan
      MORE INFO
    • TITLE: Raman Monitoring in the Petrochemical Industry
      AIR DATE: 2008-07-10
      PRESENTER INFO
      Name: Dr. Alan D. Eastman
      Title: Process Analytical Chemistry Consultant
      Company: Eastman Associates LLC
      MORE INFO
    • TITLE: Quantitative Process Raman
      AIR DATE: 2008-06-26
      PRESENTER INFO
      Name: Dr. Brian J. Marquardt
      Title: Senior Principal Engineer
      Company: Applied Physics Labs, University of Washington
      MORE INFO
    • TITLE: ATEX
      AIR DATE: 2008-04-24
      PRESENTER INFO
      Name: Joe Slater
      Title: Manager of Product Development
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Raman Sampling
      AIR DATE: 2008-02-26
      PRESENTER INFO
      Name: Dr. Ian Lewis
      Title: Marketing Manager
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
    • TITLE: Kaiser iC Raman™ V2.0
      AIR DATE: 2008-01-17
      PRESENTER INFO
      Name: Maryann Cuellar
      Title: Product Specialist
      Company: Kaiser Optical Systems, Inc.
      MORE INFO
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