Raman spectroscopy provides the chemical specificity of mid-IR spectroscopy but operates in the visible spectral region, allowing spectra to be collected without sample purging, without the use of exotic sampling cells, and in most cases, without sample preparation. The RamanRxn Systems family of instruments is based on advanced and innovative technologies to provide distinct advantages over traditional instrumentation.

The HoloPlex™ advantage, standard in all RamanRxn1 HTS systems, yields both wide spectral coverage and high spectral resolution simultaneously for improved qualitative and quantitative analysis. Qualitative analysis is faster compared to traditional scanning instruments because the entire Raman spectrum is measured simultaneously, which translates into higher sample throughput in HTS applications, real-time data collection for reaction monitoring, and faster imaging for the microprobe. This unique advantage also allows the RamanRxn Systems family of analyzers to be used for quantitative analysis. The RamanRxn1 HTS uses an optional Raman Calibration Accessory (HCA) and advanced calibration protocols, developed and demonstrated in the process arena, to ensure optimal instrument performance and calibration transferability.

The RamanRxn1 HTS, using the RamanRxn Systems spectrographic engine, provides the flexibility needed for research with the reliability expected of a proven process analyzer.

• Fast, non-contact measurements
  
• Sharp spectral peaks for qualitative and quantitative analysis
  
• Univariate or multivariate comparative analysis methods
  
• Chemical specificity of mid-IR with in situ analysis
  
• Easy sampling of solids, liquids, slurries, and emulsions
  

Screener Features

• Class I light shield
  
• LWD objectives
  
• Preprogrammed for 96- and 48-well plates
  
• Autofocus and autoexposure modes
  
• Centerable nosepiece mounts multiple objectives for high- and low-fill wellplates

• HoloPlex advantage—full spectral range data recorded at high resolution without moving parts enables analysis to be conducted in a fraction of the time of traditional analyzers
  
• LWD objectives allow analysis of deep wells (up to 18 mm)
  
• Class I light shield for unattended laser safe operation in standard laboratory environment
  
• NIR laser standard to maximize system compatibility with pharmaceutical and polymer materials
  
• Small analyzer footprint designed for use in standard laboratory work environments
  

• Analyze whole or partial wellplates
  
• Predefined 96- or 48-well formats or configure your own plate type
  
• Autofocus and autoexposure modes of analysis are standard, allowing high-quality information to be collected at each well
  
• Preprogrammed homogeneity or micro-well mapping acquisition options
  

• User-selection of reference cells (available but not required)
  
• Well comparison using univariate (peak shifts, areas, etc.) and multivariate techniques
  
• Graphical and spreadsheet outputs for expert users and technicians, including spectral display, well-comparison overlay, waterfall plots, and others.