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Raman Spectroscopy

Raman Applications
Process and PAT

Kaiser Optical Systems, Inc. offers one of the most comprehensive range of Raman products to help meet the needs of Process and PAT markets.

Kaiser has demonstrated a commitment to excellence in our products and service to our customers.  Our knowledge, gained through 17 years of 24/7 process experience working with our customers in the Process Analytical Chemistry (PAC) and Process Analytical Technology (PAT) markets, has lead to the current generation of optimized, self-checking, self-diagnosing process Raman equipment.  The combination of industry leading sampling flexibility and smart analyzers is found in the suite of RAMANRXN SYSTEMS process Raman analyzers. 

Process knowledge and understanding is key to developing and keeping a process under control.  Maintaining a process within control limits allows an “in-spec” product to be manufactured each and every time.  Process understanding is not industry specific in today’s competitive marketplace. The value of an analytical tool can be measured in many ways including “how many problems it can solve” or “what is the value of the associated savings.”  Scientifically and financially successful Raman applications have been demonstrated both at-line in the laboratory and on-line in manufacturing in PAC and PAT environments.  Contact Kaiser for a list of companies working with and applications enabled by RAMANRXN SYSTEMS Raman analyzers.

Analyzers are available for process development in general purpose areas, moveable systems for plant trials, enclosed analyzers for classified locations and to meet the European ATEX safety requirements.

Contact a Kaiser Expert to discuss your applications needs.

Further information on Process/PAT Raman applications can be found in Handbook of Raman Spectroscopy:  From Laboratory to Process Line by Ian R. Lewis and Howell G. M. Edwards, Marcel Dekker, New York, New York (2001)

Additional articles outlining the utility of Raman for pharmaceutical analysis and manufacturing can be found at the American Pharmaceutical Review website.  www.americanpharmaceuticalreview.com

 


The Formation of Phosphorus Trichloride from Phosphorus and Chlorine
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The Production of Methyl Chlorosilanes
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Monitoring the Rutile/Anatase Ratio in TiO2 Production
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Headspace Gas Analysis
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Kinetics of a Catalytic Hydrogenation Reaction
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In Situ Crystallization Monitoring
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Monitoring Grignard Production in Real Time
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Monitoring a Pharmaceutical Crystal Transformation In Situ
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Rapid Monitoring of Antisolvent Addition Crystallization and Dehydration
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Raman-Based High-Throughput Screening for Version and Polymorph Identification
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Off-Line and On-Line Raman Spectroscopy of API-Containing Extruded Films
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Optimizing a Microwave-Assisted Diels–Alder Reaction with Real-Time Analytics
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Quantifying Anhydrate/Hydrate Using Potential PAT In Situ Techniques
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Following a Process-Induced Transformation During Granulation Using In Situ Techniques
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Comparing PhAT System™ and RamanRxn1™ Approaches for the Study of Wet Granulation
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